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Thymidylate Synthase Recombinant Rabbit mAb (KU)

货号: BS45171

价格：￥ 1200

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS45171

Product Name :Thymidylate Synthase Recombinant Rabbit mAb (KU)

Swiss-Prot :P04818

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB, IHC, ICC/IF, FC, IP

Application_all :WB: 1:1000-1:5000<br />IHC: 1:100<br />ICC/IF: 1:100-1:200<br />FC: 1:20<br />IP: 1:20

Background :Thymidylate synthase catalyzes the methylation of deoxyuridylate to deoxythymidylate using, 10-methylenetetrahydrofolate (methylene-THF) as a cofactor. This function maintains the dTMP (thymidine-5-prime monophosphate) pool critical for DNA replication and repair. The enzyme has been of interest as a target for cancer chemotherapeutic agents. It is considered to be the primary site of action for 5-fluorouracil, 5-fluoro-2-prime-deoxyuridine, and some folate analogs. Expression of this gene and that of a naturally occurring antisense transcript, mitochondrial enolase superfamily member 1 (GeneID:55556), vary inversely when cell-growth progresses from late-log to plateau phase. Polymorphisms in this gene may be associated with etiology of neoplasia, including breast cancer, and response to chemotherapy. [provided by RefSeq, Aug 2017]

Product :Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Purification&Purity :Affinity Purification

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :36 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :TS; TMS; HST422

Immunogen :A synthetic peptide of human Thymidylate Synthase

Conjugate :Unconjugated

Modification :Unmodification

Western blot detection of Thymidylate Synthase in K562 cell lysates using Thymidylate Synthase antibody(1:1000 diluted).

免疫沉淀（IP）

免疫组织化学（IHC）