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USP13 Recombinant Rabbit mAb (KU)

货号: BS45151

价格：￥ 1200

货期：现货（1-2个工作日）

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详细信息检测数据实验指南文献

No. :BS45151

Product Name :USP13 Recombinant Rabbit mAb (KU)

Swiss-Prot :Q92995

Host :Rabbit

Reactivity :Human, Mouse

Applications :WB, ICC/IF, FC, IP

Application_all :WB: 1:1000-1:5000<br />ICC/IF: 1:20-1:50<br />FC: 1:100-1:500<br />IP: 1:20-1:50

Background :Deubiquitinase that mediates deubiquitination of target proteins such as BECN1, MITF, SKP2 and USP10 and is involved in various processes such as autophagy and endoplasmic reticulum-associated degradation (ERAD). Component of a regulatory loop that controls autophagy and p53/TP53 levels: mediates deubiquitination of BECN1, a key regulator of autophagy, leading to stabilize the PIK3C3/VPS34-containing complexes. Also deubiquitinates USP10, an essential regulator of p53/TP53 stability. In turn, PIK3C3/VPS34-containing complexes regulate USP13 stability, suggesting the existence of a regulatory system by which PIK3C3/VPS34-containing complexes regulate p53/TP53 protein levels via USP10 and USP13.

Product :Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Purification&Purity :Affinity Purification

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :97 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :ISOT3; IsoT-3

Immunogen :A synthetic peptide of human USP13

Conjugate :Unconjugated

Modification :Unmodification

Western blot detection of USP13 in U2OS cell lysates using USP13 antibody(1:500 diluted).

免疫沉淀（IP）

免疫组织化学（IHC）