Product Name :VCAM1 Recombinant Rabbit mAb (KU)
Reactivity :Human, Mouse, Rat
Applications :WB, IHC, ICC/IF, FC, IP
Background :This gene is a member of the Ig superfamily and encodes a cell surface sialoglycoprotein expressed by cytokine-activated endothelium. This type I membrane protein mediates leukocyte-endothelial cell adhesion and signal transduction, and may play a role in the development of artherosclerosis and rheumatoid arthritis. Three alternatively spliced transcripts encoding different isoforms have been described for this gene. [provided by RefSeq, Dec 2010]