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E2F1 Recombinant Rabbit mAb (KU)

货号: BS45122

价格：￥ 1200

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS45122

Product Name :E2F1 Recombinant Rabbit mAb (KU)

Swiss-Prot :Q01094

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB, IHC, ICC/IF, FC, IP

Application_all :WB: 1:1000<br />IHC: 1:20<br />ICC/IF: 1:50<br />FC: 1:20<br />IP: 1:20

Background :The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F2 and E2F3, have an additional cyclin binding domain. This protein binds preferentially to retinoblastoma protein pRB in a cell-cycle dependent manner. It can mediate both cell proliferation and p53-dependent/independent apoptosis. [provided by RefSeq, Jul 2008]

Product :Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Purification&Purity :Affinity Purification

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :70 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :RBP3; E2F-1; RBAP1; RBBP3

Immunogen :A synthetic peptide of human E2F1

Conjugate :Unconjugated

Modification :Unmodification

Western blot detection of E2F1 in C6,3T3 cell lysates using E2F1 antibody(1:1000 diluted).

免疫沉淀（IP）

免疫组织化学（IHC）