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p68 RNA Helicase (phospho-Y593) polyclonal antibody（KU）

货号: BS4496

价格：￥ 1350

货期：现货（1-2个工作日）

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No. :BS4496

Product Name :p68 RNA Helicase (phospho-Y593) polyclonal antibody（KU）

Swiss-Prot :P17844

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB

Application_all :WB: 1:500~1:1000

Background :p68 RNA Helicase is a nuclear protein that exhibits RNA-dependent ATPase activity. Phosphorylation by protein kinase C inhibits p68 RNA Helicase activity. p68 RNA Helicase appears to play a role in organ differentiation during development. Furthermore, p68 RNA Helicase is expressed in early neural development and in various mesodermal tissues in a number of different chordate embryos. At the cellular level, the expression levels of p68 RNA Helicase increase in serum-induced quiescent cell lines. p68 RNA Helicase may function as a coactivator for estrogen receptor α. Additionally, p68 RNA Helicase associates with transcriptional coactivators CBP and p300. p68 RNA Helicase localizes to the nucleus under normal conditions. During late telophase, p68 RNA Helicase and fibrillarin co-localize to nascent nucleoli. p68 RNA Helicase may function as a heterodimer with p72 RNA Helicase.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :p68 RNA Helicase (phospho-Y593) polyclonal antibody detects endogenous levels of p68 RNA Helicase protein only when phosphorylated at Tyr593.

BiowMW :~ 68 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :ATP dependent RNA helicase DDX5; DDX 5; Ddx5; DDX5; DEAD (Asp Glu Ala Asp) box helicase 5; DEAD (Asp Glu Ala Asp) box polypeptide 5; DEAD box 5; DEAD box protein 5; DEAD/H (Asp Glu Ala Asp/His) box polypeptide 5 (RNA helicase; 68kD); DEAD/H (Asp Glu Ala Asp/His) box polypeptide 5; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 5 (RNA helicase 68kDa); DEAD/H box-5 (RNA helicase 68kD); DKFZp686J01190; G17P1; HELR; HLR 1; HLR1; HUMP68; P68; P68; p68 RNA he

Immunogen :Synthetic peptide derived from human p68 RNA Helicase around the phosphorylation site of Y593.

Conjugate :Unconjugated

Modification :Phosphorylation

Western blot (WB) analysis of p68 RNA Helicase (phospho-Y593) polyclonal antibody at 1:500 dilution Lane1:MCF-7 whole cell lysate(40µg) Lane2:A375 whole cell lysate(40µg) Lane3:U-87MG whole cell lysate(40µg) Lane4:CT-26 whole cell lysate(40µg) Lane5:C6 whole cell lysate(40µg)