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TK (phospho-S13) polyclonal antibody（KU）

货号: BS4365

价格：￥ 1350

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS4365

Product Name :TK (phospho-S13) polyclonal antibody（KU）

Swiss-Prot :P04183

Host :Rabbit

Reactivity :Human

Applications :WB

Application_all :WB: 1:500~1:1000

Background :Thymidine Kinase (TK1) is a highly conserved phosphotransferase that is present in most living cells. Thymidine Kinase catalyzes the phosphorylation reaction: deoxythymidine + ATP = deoxythymidine 5'-phosphate + ADP; it is thus involved in the reaction chain to introduce deoxythymidine into the DNA. Thymidine kinase is required for the action of many antiviral drugs, such as azidothymidine (AZT), and is is also used to select hybridoma cell lines in the production of monoclonal antibodies. Thymidine Kinase has many clinical applications as it is only present in anticipation of cell division.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :TK (phospho-S13) polyclonal antibody detects endogenous levels of Thymidine Kinase protein only when phosphorylated at Ser13.

BiowMW :~ 28 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :TK1; Thymidine Kinase; TK2

Immunogen :Synthetic peptide derived from human TK around the phosphorylation site of S13.

Conjugate :Unconjugated

Modification :Phosphorylated

Western blot (WB) analysis of p-Thymidine Kinase (S13) pAb at 1:500 dilution Lane1:Myla2059 whole cell lysate(40ug) Lane2:HuT78 whole cell lysate(40ug) Lane3:K562 whole cell lysate(40ug)