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Sp1 (phospho-T453) polyclonal antibody

货号: BS4363
价格 1350
货期 现货(1-2个工作日)
25ul 50ul 100ul 200ul
No. :BS4363
Product Name :Sp1 (phospho-T453) polyclonal antibody
Swiss-Prot :P08047
Host :Rabbit
Reactivity :Human,Mouse,Rat
Applications :IHC
Application_all :IHC: 1:50~1:200
Background :Sp1 is a sequence-specific transcription factor that recognizes GGGGCGGGGC and closely related sequences, which are often referred to as GC boxes. Sp1 was initially identified as a HeLa cell-derived factor that selectively activates in vitro transcription from the SV40 promoter and binds to the multiple GC boxes in the 21 bp repeated elements in SV40. The sequence specificity of DNA binding is conferred by Zn (II) fingers, whereas a different region of Sp1 appears to regulate the affinity of DNA binding. Sp1 belongs to a subgroup of transcription factors that are phosphorylated upon binding to promoter sequences.
Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :p-Sp1 (T453) polyclonal antibody detects endogenous levels of Sp1 protein only when phosphorylated at Thr453
BiowMW :~ 90 kDa
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :Transcription factor Sp1; SP1; TSFP1
Immunogen :Synthetic phosphopeptide derived from human Sp1 around the phosphorylation site of Threonine 453.
Conjugate :Unconjugated
Modification :Phosphorylation
  • The membrane complement regulatory protein CD59 promotes tumor growth and predicts poor prognosis in breast cancer
    JournalInternational Journal Of Oncology
    ApplicationWB
    IF3.571
    SpeciesHuman

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400-660-9091

电话:025-68037686

地址:江苏生命科技创新园F6幢1层

订购:nanjing03@biogot.com

服务:biorase01@biogot.com

合作:lvyun@biogot.com

支持:may@biogot.com