Product Name :Crotonyl-Histone H4 (Lys8) Recombinant Rabbit mAb (KU)
Reactivity :Human, Mouse, Rat
Applications :WB, IHC, ICC/IF
Background :Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
