Product Name :Citrulline-Histone H3 (Arg8) Recombinant Rabbit mAb (KU)
Reactivity :Human, Mouse, Rat
Applications :WB, ICC/IF, FC, IP
Application_all :WB: 1:1000<br />ICC/IF: 1:100<br />FC: 1:200<br />IP: 1:20
Background :Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Product :Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
Purification&Purity :Affinity Purification
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :H3/A; H3FA
Immunogen :A synthetic citrullinepeptide corresponding to residues surrounding Arg8 of human Histone H3
Modification :Unmodification
