Product Name :Phospho-160 kD Neurofilament Medium (Ser614/Ser619) Recombinant Rabbit mAb (KU)
Application_all :WB: 1:1000<br />IHC: 1:50
Background :Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the medium neurofilament protein. This protein is commonly used as a biomarker of neuronal damage. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008]
Product :Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
Purification&Purity :Affinity Purification
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :NFM; NEF3; NF-M
Immunogen :A synthetic phosphopeptide corresponding to residues surrounding
Ser614/Ser619 of human 160 kD Neurofilament Medium
Modification :Phosphorylated