Product Name :Phospho-MYL12A (Thr17/Ser18) Recombinant Rabbit mAb (KU)
Reactivity :Human, Mouse, Rat
Application_all :WB: 1:1000
Background :This gene encodes a nonsarcomeric myosin regulatory light chain. This protein is activated by phosphorylation and regulates smooth muscle and non-muscle cell contraction. This protein may also be involved in DNA damage repair by sequestering the transcriptional regulator apoptosis-antagonizing transcription factor (AATF)/Che-1 which functions as a repressor of p53-driven apoptosis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 8.[provided by RefSeq, Dec 2014]
Product :Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
Purification&Purity :Affinity Purification
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :MLCB; MRCL3; MRLC3; MYL2B; MLC-2B; HEL-S-24
Immunogen :A synthetic phosphopeptide corresponding to residues surrounding Thr17/Ser18 of human MYL12A
Modification :Phosphorylated
