Product Name :Phospho-GABA B Receptor 2/GABBR2 (Ser884) Recombinant Rabbit mAb (KU)
Applications :WB,ICC/IF,IP
Application_all :WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/20
Background :The multi-pass membrane protein encoded by this gene belongs to the G-protein coupled receptor 3 family and GABA-B receptor subfamily. The GABA-B receptors inhibit neuronal activity through G protein-coupled second-messenger systems, which regulate the release of neurotransmitters, and the activity of ion channels and adenylyl cyclase. This receptor subunit forms an active heterodimeric complex with GABA-B receptor subunit 1, neither of which is effective on its own. Allelic variants of this gene have been associated with nicotine dependence.[provided by RefSeq, Jan 2010]
Product :Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification&Purity :Affinity Purified
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
BiowMW :Calculated MW: 124 kDa; Observed MW: 124 kDa
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :VCL; Vinculin; Metavinculin
Immunogen :A synthesized peptide derived from human Vinculin
