Product Name :Phospho-EGFR (Tyr1086) Recombinant Rabbit mAb (KU)
Applications :WB,ICC/IF,IP
Application_all :WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/20
Background :The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. EGFR is a component of the cytokine storm which contributes to a severe form of coronavirus disease 2019 (COVID-19) resulting from infection with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). [provided by RefSeq, Jun 2020]
Product :Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification&Purity :Affinity Purified
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
BiowMW :Calculated MW: 124 kDa; Observed MW: 124 kDa
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :VCL; Vinculin; Metavinculin
Immunogen :A synthesized peptide derived from human Vinculin
