Product Name :Phospho-MARCKS (Ser158) Recombinant Rabbit mAb (KU)
Reactivity :Human, Mouse, Rat
Application_all :WB: 1:1000-1:5000
Background :The protein encoded by this gene is a substrate for protein kinase C. It is localized to the plasma membrane and is an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and with the plasma membrane, leading to its presence in the cytoplasm. The protein is thought to be involved in cell motility, phagocytosis, membrane trafficking and mitogenesis. [provided by RefSeq, Jul 2008]
Product :Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
Purification&Purity :Affinity Purification
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :MACS; 80K-L; PKCSL; PRKCSL
Immunogen :A synthetic phosphopeptide corresponding to residues surrounding Ser158 of human MARCKS
Modification :Phosphorylated