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Phospho-Rb (Thr373) Recombinant Rabbit mAb (KU)

货号: BS43262

价格：￥ 1200

货期：现货（1-2个工作日）

25ul 50ul 100ul

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS43262

Product Name :Phospho-Rb (Thr373) Recombinant Rabbit mAb (KU)

Swiss-Prot :P06400

Host :Rabbit

Reactivity :Human

Applications :WB,IHC,ICC/IF,IP

Background :The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. [provided by RefSeq, Jul 2008]