Product Name :Phospho-ZAP70 (Tyr292) Recombinant Rabbit mAb (KU)
Applications :WB,ICC/IF,FC
Application_all :WB: 1/500-1/1000 IF: 1/50-1/200 FC: 1/50-1/100
Background :This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Product :Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification&Purity :Affinity Purified
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
BiowMW :Calculated MW: 45 kDa; Observed MW: 45 kDa
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :PGKA; MIG10; HEL-S-68p
Immunogen :A synthesized peptide derived from human PGK1
