Product Name :Phospho-alpha Synuclein (Ser129) Recombinant Rabbit mAb (KU)
Reactivity :Human, Mouse, Rat
Applications :WB,IHC,ICC/IF
Application_all :WB: 1:1000<br />IHC: 1:100<br />ICC/IF: 1:20-1:100
Background :Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene. [provided by RefSeq, Feb 2016]
Product :Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
Purification&Purity :Affinity Purification
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :PD1; NACP; PARK1; PARK4
Immunogen :A synthetic phosphopeptide corresponding to residues surrounding
Ser129 of human alpha Synuclein
Modification :Phosphorylated
