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Phospho-MCM2 (Ser108) Recombinant Rabbit mAb (KU)

货号: BS43174

价格：￥ 1200

货期：现货（1-2个工作日）

25ul 50ul 100ul

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS43174

Product Name :Phospho-MCM2 (Ser108) Recombinant Rabbit mAb (KU)

Swiss-Prot :P49736

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB,ICC/IF,IP

Application_all :WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/20

Background :The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein forms a complex with MCM4, 6, and 7, and has been shown to regulate the helicase activity of the complex. This protein is phosphorylated, and thus regulated by, protein kinases CDC2 and CDC7. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined. [provided by RefSeq, Oct 2012]

Product :Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :Calculated MW: 124 kDa; Observed MW: 124 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :VCL; Vinculin; Metavinculin

Immunogen :A synthesized peptide derived from human Vinculin

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of Vinculin in Jurkat, COS7, HepG2, U2OS, Hela lysates using Vinculin antibody.

免疫沉淀（IP）