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Phospho-Rb (Ser811) Recombinant Rabbit mAb (KU)

货号: BS43173

价格：￥ 1200

货期：现货（1-2个工作日）

25ul 50ul 100ul

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS43173

Product Name :Phospho-Rb (Ser811) Recombinant Rabbit mAb (KU)

Swiss-Prot :P06400

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB,ICC/IF

Application_all :WB: 1/500-1/1000 IF: 1/50-1/200

Background :The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. [provided by RefSeq, Jul 2008]

Product :Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :Calculated MW: 15 kDa; Observed MW: 15 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :H3 histone; family 3A; H3 histone; family 3B (H3.3B); H3.3A; H3.3B; H33; H3F3; H3F3A; H3F3B; Histone H3.3

Immunogen :Human Phospho-Histone H3(Ser10) synthetic peptide conjugated to KLH.

Conjugate :Unconjugated

Modification :Phosphorylated

Western blot analysis of Phospho-Histone H3 in HeLa lysates, untreated or 1mM hydroxyurea treated for 5 hours, using Phospho-Histone H3 antibody.

免疫沉淀（IP）