产品类别

联系我们

电话:025-68037686

地址:江苏生命科技创新园F6幢1层

订购:nanjing03@biogot.com

服务:biorase01@biogot.com

合作:lvyun@biogot.com

支持:may@biogot.com

Phospho-PKC (Thr514) Recombinant Rabbit mAb (KU)

货号: BS43172

价格：￥ 1200

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

抗体定制服务咨询

说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS43172

Product Name :Phospho-PKC (Thr514) Recombinant Rabbit mAb (KU)

Swiss-Prot :P05129

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB,IHC,IP

Application_all :WB: 1:1000-1:5000<br />IHC: 1:20-1:100<br />IP: 1:20

Background :Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells. The protein encoded by this gene is one of the PKC family members. This protein kinase is expressed solely in the brain and spinal cord and its localization is restricted to neurons. It has been demonstrated that several neuronal functions, including long term potentiation (LTP) and long term depression (LTD), specifically require this kinase. Knockout studies in mice also suggest that this kinase may be involved in neuropathic pain development. Defects in this protein have been associated with neurodegenerative disorder spinocerebellar ataxia-14 (SCA14). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2015]

Product :Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Purification&Purity :Affinity Purification

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :78-85 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :PKCC; PKCG; SCA14; PKC-gamma

Immunogen :A synthetic phosphopeptide corresponding to residues surrounding Thr514 of human PKC

Conjugate :Unconjugated

Modification :Phosphorylated

Western blot detection of Phospho-PKC gamma (Thr514) in C6,Hela cell lysates using Phospho-PKC gamma (Thr514) antibody(1:1000 diluted).

免疫沉淀（IP）

免疫组织化学（IHC）