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Phospho-Glucocorticoid Receptor (Ser226) Recombinant Rabbit mAb (KU)

货号: BS43152

价格：￥ 1200

货期：现货（1-2个工作日）

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详细信息检测数据实验指南文献

No. :BS43152

Product Name :Phospho-Glucocorticoid Receptor (Ser226) Recombinant Rabbit mAb (KU)

Swiss-Prot :P04150

Host :Rabbit

Reactivity :Human

Applications :WB,IHC

Application_all :WB: 1:1000<br />IHC: 1:100

Background :This gene encodes glucocorticoid receptor, which can function both as a transcription factor that binds to glucocorticoid response elements in the promoters of glucocorticoid responsive genes to activate their transcription, and as a regulator of other transcription factors. This receptor is typically found in the cytoplasm, but upon ligand binding, is transported into the nucleus. It is involved in inflammatory responses, cellular proliferation, and differentiation in target tissues. Mutations in this gene are associated with generalized glucocorticoid resistance. Alternative splicing of this gene results in transcript variants encoding either the same or different isoforms. Additional isoforms resulting from the use of alternate in-frame translation initiation sites have also been described, and shown to be functional, displaying diverse cytoplasm-to-nucleus trafficking patterns and distinct transcriptional activities (PMID:15866175). [provided by RefSeq, Feb 2011]

Product :Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Purification&Purity :Affinity Purification

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :94 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :GR; GCR; GRL; GCCR; GCRST

Immunogen :A synthetic phosphopeptide corresponding to residues surrounding Ser226 of human Glucocorticoid Receptor

Conjugate :Unconjugated

Modification :Phosphorylated

Western blot detection of Glucocorticoid Receptor (phospho-Ser226) in Hela,A549,C6 cell lysates using Glucocorticoid Receptor (phospho-Ser226) antibody(1:1000 diluted).