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Phospho-PKA RII alpha (Ser99) Recombinant Rabbit mAb (KU)

货号: BS43148

价格：￥ 1200

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS43148

Product Name :Phospho-PKA RII alpha (Ser99) Recombinant Rabbit mAb (KU)

Swiss-Prot :P13861

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB, IHC, ICC/IF, IP

Application_all :WB: 1:1000<br />IHC: 1:100<br />ICC/IF: 1:100<br />IP: 1:20

Background :cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. The protein encoded by this gene is one of the regulatory subunits. This subunit can be phosphorylated by the activated catalytic subunit. It may interact with various A-kinase anchoring proteins and determine the subcellular localization of cAMP-dependent protein kinase. This subunit has been shown to regulate protein transport from endosomes to the Golgi apparatus and further to the endoplasmic reticulum (ER). [provided by RefSeq, Jul 2008]

Product :Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Purification&Purity :Affinity Purification

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :50 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :PKR2; PRKAR2

Immunogen :A synthetic phosphopeptide corresponding to residues surrounding Ser99 of human PKA R2

Conjugate :Unconjugated

Modification :Phosphorylated

Western blot detection of Phospho-PKA RIIalpha (Ser99) in Rat Brain,C6 cell lysates using Phospho-PKA RIIalpha (Ser99) antibody(1:1000 diluted).

免疫沉淀（IP）

免疫组织化学（IHC）