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Phospho-E Cadherin (Ser838/Ser840) Recombinant Rabbit mAb (KU)

货号: BS43145

价格：￥ 1200

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS43145

Product Name :Phospho-E Cadherin (Ser838/Ser840) Recombinant Rabbit mAb (KU)

Swiss-Prot :P12830

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB,IHC,IP

Application_all :WB: 1:2000-1:10000<br />IHC: 1:20<br />IP: 1:20

Background :This gene encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion protein is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function of this gene is thought to contribute to cancer progression by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. This gene is present in a gene cluster with other members of the cadherin family on chromosome 16. [provided by RefSeq, Nov 2015]

Product :Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Purification&Purity :Affinity Purification

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :135 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :UVO; CDHE; ECAD; LCAM; Arc-1; BCDS1; CD324

Immunogen :A synthetic phosphopeptide corresponding to residues surrounding Ser838/Ser840 of human E Cadherin

Conjugate :Unconjugated

Modification :Phosphorylated

Western blot detection of E Cadherin (phospho-Ser838/Ser840) in HepG2,U2OS,U251,Lncap using E Cadherin (phospho-Ser838/Ser840) antibody(1:1000 diluted)