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Phospho-Rb (Thr356) Recombinant Rabbit mAb (KU)

货号: BS43140

价格：￥ 1200

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS43140

Product Name :Phospho-Rb (Thr356) Recombinant Rabbit mAb (KU)

Swiss-Prot :P06400

Host :Rabbit

Reactivity :Human

Applications :WB,IHC,IP

Application_all :WB: 1:1000<br />IHC: 1:50<br />IP: 1:20

Background :The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. [provided by RefSeq, Jul 2008]

Product :Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Purification&Purity :Affinity Purification

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :110 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :RB; pRb; OSRC; pp110; p105-Rb; PPP1R130; p110-RB1

Immunogen :A synthetic phosphopeptide corresponding to residues surrounding Thr356 of human Rb

Conjugate :Unconjugated

Modification :Phosphorylated

Western blot detection of Rb (phospho-Thr356) in HL-60,U2OS,C6 using Rb (phospho-Thr356) antibody(1:1000 diluted)

免疫沉淀（IP）

免疫组织化学（IHC）