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Phospho-Rb2 p130 (Ser952) Recombinant Rabbit mAb (KU)

货号: BS43136

价格：￥ 1200

货期：现货（1-2个工作日）

25ul 50ul 100ul

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No. :BS43136

Product Name :Phospho-Rb2 p130 (Ser952) Recombinant Rabbit mAb (KU)

Swiss-Prot :Q08999

Host :Rabbit

Reactivity :Human, Mouse

Applications :WB,IHC,ICC/IF

Background :Key regulator of entry into cell division. Directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation. Recruits and targets histone methyltransferases KMT5B and KMT5C, leading to epigenetic transcriptional repression. Controls histone H4 'Lys-20' trimethylation. Probably acts as a transcription repressor by recruiting chromatin-modifying enzymes to promoters.