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Phospho-Rb2 p130 (Ser952) Recombinant Rabbit mAb (KU)

货号: BS43136

价格：￥ 1200

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS43136

Product Name :Phospho-Rb2 p130 (Ser952) Recombinant Rabbit mAb (KU)

Swiss-Prot :Q08999

Host :Rabbit

Reactivity :Human, Mouse

Applications :WB,IHC,ICC/IF

Application_all :WB: 1:2000-1:10000<br />IHC: 1:20-1:100<br />ICC/IF: 1:20-1:100

Background :Key regulator of entry into cell division. Directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation. Recruits and targets histone methyltransferases KMT5B and KMT5C, leading to epigenetic transcriptional repression. Controls histone H4 'Lys-20' trimethylation. Probably acts as a transcription repressor by recruiting chromatin-modifying enzymes to promoters.

Product :Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Purification&Purity :Affinity Purification

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :130 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Rb2; P130

Immunogen :A synthetic phosphopeptide corresponding to residues surrounding Ser952 of human Rb2 p130

Conjugate :Unconjugated

Modification :Phosphorylated

Western blot detection of Rb2 p130 (Phospho-Ser952) in K562,Hela cell lysates using Rb2 p130 (Phospho-Ser952) antibody(1:1000 diluted).

免疫沉淀（IP）

免疫组织化学（IHC）