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Phospho-c-Met (Tyr1349) Recombinant Rabbit mAb (KU)

货号: BS43125

价格：￥ 1200

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS43125

Product Name :Phospho-c-Met (Tyr1349) Recombinant Rabbit mAb (KU)

Swiss-Prot :P08581

Host :Rabbit

Reactivity :Human

Applications :WB,IHC,IP

Application_all :WB: 1:1000<br />IHC: 1:20<br />IP: 1:20

Background :This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that are linked via disulfide bonds to form the mature receptor. Further processing of the beta subunit results in the formation of the M10 peptide, which has been shown to reduce lung fibrosis. Binding of its ligand, hepatocyte growth factor, induces dimerization and activation of the receptor, which plays a role in cellular survival, embryogenesis, and cellular migration and invasion. Mutations in this gene are associated with papillary renal cell carcinoma, hepatocellular carcinoma, and various head and neck cancers. Amplification and overexpression of this gene are also associated with multiple human cancers. [provided by RefSeq, May 2016]

Product :Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Purification&Purity :Affinity Purification

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :170140 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :HGFR; AUTS9; RCCP2; c-Met; DFNB97

Immunogen :A synthetic phosphopeptide corresponding to residues surrounding Tyr1349 of human Met

Conjugate :Unconjugated

Modification :Phosphorylated

Western blot detection of Met (c-Met) (phospho-Tyr1349) in Hela,A549 cell lysates using Met (c-Met) (phospho-Tyr1349) antibody(1:1000 diluted).

免疫沉淀（IP）

免疫组织化学（IHC）