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Phospho-ATP citrate lyase (Thr447/Ser451) Recombinant Rabbit mAb (KU)

货号: BS43101

价格：￥ 1200

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS43101

Product Name :Phospho-ATP citrate lyase (Thr447/Ser451) Recombinant Rabbit mAb (KU)

Swiss-Prot :P53396

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB,ICC/IF,IP

Application_all :WB: 1:1000<br />ICC/IF: 1:50<br />IP: 1:20

Background :ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Dec 2014]

Product :Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Purification&Purity :Affinity Purification

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :121 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :ACL; ATPCL; CLATP

Immunogen :A synthetic phosphopeptide corresponding to residues surrounding Thr447/Ser451 of human ATP citrate lyase

Conjugate :Unconjugated

Modification :Phosphorylated

Western blot detection of Phospho-ATP citrate lyase (Thr447+Ser451) in K562 cell lysates using Phospho-ATP citrate lyase (Thr447+Ser451) antibody(1:1000 diluted).