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Phospho-Amyloid Precursor Protein (Thr743) Recombinant Rabbit mAb (KU)

货号: BS43089

价格：￥ 1200

货期：现货（1-2个工作日）

25ul 50ul 100ul

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS43089

Product Name :Phospho-Amyloid Precursor Protein (Thr743) Recombinant Rabbit mAb (KU)

Swiss-Prot :P05067

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB,ICC/IF,IP

Application_all :WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/20

Background :This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. In addition, two of the peptides are antimicrobial peptides, having been shown to have bacteriocidal and antifungal activities. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Aug 2014]

Product :Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :Calculated MW: 124 kDa; Observed MW: 124 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :VCL; Vinculin; Metavinculin

Immunogen :A synthesized peptide derived from human Vinculin

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of Vinculin in Jurkat, COS7, HepG2, U2OS, Hela lysates using Vinculin antibody.

免疫沉淀（IP）