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Phospho-p27 KIP 1 (Ser10) Recombinant Rabbit mAb (KU)

货号: BS43083

价格：￥ 1200

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS43083

Product Name :Phospho-p27 KIP 1 (Ser10) Recombinant Rabbit mAb (KU)

Swiss-Prot :P46527

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB,IHC,IP

Application_all :WB: 1:1000<br />IHC: 1:50-1:200<br />IP: 1:20

Background :This gene encodes a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state. Mutations in this gene are associated with multiple endocrine neoplasia type IV (MEN4). [provided by RefSeq, Apr 2014]

Product :Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Purification&Purity :Affinity Purification

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :27 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :KIP1; MEN4; CDKN4; MEN1B; P27KIP1

Immunogen :A synthetic phosphopeptide corresponding to residues surrounding Ser10 of human p27 KIP 1

Conjugate :Unconjugated

Modification :Phosphorylated

Western blot detection of Phospho-p27 KIP 1 (Ser10) in C6 cell lysates using Phospho-p27 KIP 1 (Ser10) antibody(1:1000 diluted).

免疫沉淀（IP）

免疫组织化学（IHC）