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Phospho-ATF2 (Thr71) Recombinant Rabbit mAb (KU)

货号: BS43047

价格：￥ 1200

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS43047

Product Name :Phospho-ATF2 (Thr71) Recombinant Rabbit mAb (KU)

Swiss-Prot :P15336

Host :Rabbit

Reactivity :Human, Mouse

Applications :WB, ICC/IF, IP

Application_all :WB: 1:1000<br />ICC/IF: 1:100<br />IP: 1:20

Background :This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. It forms a homodimer or a heterodimer with c-Jun and stimulates CRE-dependent transcription. This protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. The encoded protein may also be involved in cell's DNA damage response independent of its role in transcriptional regulation. Several alternatively spliced transcript variants have been found for this gene [provided by RefSeq, Jan 2014]

Product :Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Purification&Purity :Affinity Purification

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :70 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :HB16; CREB2; TREB7; CREB-2; CRE-BP1

Immunogen :A synthetic phosphopeptide corresponding to residues surrounding Thr71 of human ATF2

Conjugate :Unconjugated

Modification :Phosphorylated

Western blot detection of Phospho-ATF2 (Thr71) in 3T3,Hela cell lysates using Phospho-ATF2 (Thr71) antibody(1:1000 diluted).

免疫沉淀（IP）

免疫组织化学（IHC）