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Phospho-MSK1 (Ser360) Recombinant Rabbit mAb (KU)

货号: BS43026

价格：￥ 1200

货期：现货（1-2个工作日）

25ul 50ul 100ul

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS43026

Product Name :Phospho-MSK1 (Ser360) Recombinant Rabbit mAb (KU)

Swiss-Prot :O75582

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB,ICC/IF,IP

Application_all :WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/20

Background :Serine/threonine-protein kinase that is required for the mitogen or stress-induced phosphorylation of the transcription factors CREB1 and ATF1 and for the regulation of the transcription factors RELA, STAT3 and ETV1/ER81, and that contributes to gene activation by histone phosphorylation and functions in the regulation of inflammatory genes. Phosphorylates CREB1 and ATF1 in response to mitogenic or stress stimuli such as UV-C irradiation, epidermal growth factor (EGF) and anisomycin. Plays an essential role in the control of RELA transcriptional activity in response to TNF and upon glucocorticoid, associates in the cytoplasm with the glucocorticoid receptor NR3C1 and contributes to RELA inhibition and repression of inflammatory gene expression.

Product :Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :Calculated MW: 124 kDa; Observed MW: 124 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :VCL; Vinculin; Metavinculin

Immunogen :A synthesized peptide derived from human Vinculin

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of Vinculin in Jurkat, COS7, HepG2, U2OS, Hela lysates using Vinculin antibody.

免疫沉淀（IP）