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NFkB-p65 (phospho-S536) polyclonal antibody（KU）

货号: BS4138

价格：￥ 1350

货期：现货（1-2个工作日）

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详细信息检测数据实验指南文献

No. :BS4138

Product Name :NFkB-p65 (phospho-S536) polyclonal antibody（KU）

Swiss-Prot :Q04206

Host :Rabbit

Reactivity :Human

Applications :WB

Application_all :WB: 1:500~1:1000 IHC: 1:50~1:200 IP: 1:50~1:200

Background :p65 is a subunit of the nuclear factor kappa B. The transcription factor NFkB is widely recognized as a critical mediator of immune and inflammatory responses. In most cell types, NFkB is found in the cytoplasm where it is associated with an inhibitory prd in many tissues. A high proportion of spontaneous NIH/3T3 transformants overexpress c-Met and by transfection analysis the c-Met proto-oncogene has been shown to exhibittransforming activity.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :p-NFκB-p65 (S536) polyclonal antibody detects endogenous levels of NFκB-p65 p53 protein when phosphorylated at Ser536.

BiowMW :~ 65 kDa

Note :For research use only, not for use in diagnostic procedure.

Pathway :NF-kB Signaling,NF-kB Signaling,Immune Cell Signaling,Signaling Pathways Activating p38 MAP KinaseSTING Signaling,T cell receptor signaling,Contribution of Soluble Factors to EMT,

Alternative Name :p65; p65 NF kappaB; p65 NFkB; RELA; NFKB P65; Transcription Factor p65; Nuclear factor NF-kappa-B p65 subunit; NFkB-p65; NFKB3

Immunogen :Synthetic phosphopeptide derived from human NFkB-p65 around the phosphorylation site of Serine 536.

Conjugate :Unconjugated

Modification :Phosphorylation

Western blot (WB) analysis of p-NFKB-p65(S536) pAb at 1:500 dilution Lane1:HCT116 whole cell lysate(40ug) Lane2:A2780 whole cell lysate(40ug) Lane3:A549 whole cell lysate(40ug)

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