Product Name :Granzyme B Rabbit monoclonal antibody（KU）
Applications :IHC ICC/IF IP
Application_all :IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:50
Background :This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.
Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Purification&Purity :Affinity-chromatography
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Granzyme B Antibody detects endogenous levels of total Granzyme B
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :Granzyme B; Cathepsin G-like 1; CTSGL1; Lymphocyte protease; Fragmentin-2; Granzyme-2; Human lymphocyte protein; SECT; GZMB; CGL1; CSPB; CTLA1, GRB;
Immunogen :A synthesized peptide derived from human Granzyme B
