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Phospho-Raf1 (S43) Rabbit monoclonal antibody（KU）

货号: BS40359

价格：￥ 1200

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS40359

Product Name :Phospho-Raf1 (S43) Rabbit monoclonal antibody（KU）

Swiss-Prot :P04049

Host :Rabbit

Reactivity :Human Mouse Rat

Applications :WB

Application_all :WB 1:500~1:1000

Background :Raf-1 is a MAP kinase kinase kinase (MAP3K) which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated Raf-1 can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2 which in turn phosphorylate to activate the serine/threonine specific protein kinases ERK1 and ERK2. Activated ERKs are pleiotropic effectors of cell physiology and play an important role in the control of gene expression involved in the cell division cycle, apoptosis, cell differentiation and cell migration.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Purification&Purity :Affinity-chromatography

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Phospho-Raf1 (S43) Antibody detects endogenous levels of total Phospho-Raf1 (S43)

BiowMW :73kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :C-Raf; CRAF; Protein kinase raf 1; RAF1; Raf proto-oncogene serine/threonine-protein kinase; kinase Raf1;

Immunogen :A synthesized peptide derived from human Phospho-Raf1 (S43)

Conjugate :Unconjugated

Modification :Phosphorylated

Western blot analysis of Phospho-Raf1 (S43) expression in (1) HeLa cell lysate treated with LP; (2) HeLa cell lysate.

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