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Phospho-AMPK alpha 2 (S345) Rabbit monoclonal antibody（KU）

货号: BS40313

价格：￥ 1200

货期：现货（1-2个工作日）

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详细信息检测数据实验指南文献

No. :BS40313

Product Name :Phospho-AMPK alpha 2 (S345) Rabbit monoclonal antibody（KU）

Swiss-Prot :P54646

Host :Rabbit

Reactivity :Human Mouse Rat

Applications :WB

Application_all :WB 1:1000~1:2000

Background :AMP-activated protein kinase (AMPK) is highly conserved from yeast to plants and animals and plays a key role in the regulation of energy homeostasis. AMPK is a heterotrimeric complex composed of a catalytic α subunit and regulatory β and γ subunits, each of which is encoded by two or three distinct genes (α1, 2; β1, 2; γ1, 2, 3). The kinase is activated by an elevated AMP/ATP ratio due to cellular and environmental stress, such as heat shock, hypoxia, and ischemia.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Purification&Purity :Affinity-chromatography

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Phospho-AMPK alpha 2 (S345) Antibody detects endogenous levels of Phospho-AMPK alpha 2 (S345)

BiowMW :64kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :ACACA kinase; Acetyl-CoA carboxylase kinase; AMPK subunit alpha-2; AMPK2; AMPKalpha2; HMGCR kinase; Hydroxymethylglutaryl-CoA reductase kinase; PRKAA; PRKAA2;

Immunogen :A synthesized peptide derived from human AMPK alpha 2

Conjugate :Unconjugated

Modification :Phosphorylated

Western blot analysis of Phospho-AMPK alpha 2 (S345) expression in (1) 293T cell lysate treated with Lambda Phosphatase; (2) 293T cell lysate.

Activation of the AMPK/Nrf2 pathway ameliorates LPS-induced acute lung injury by inhibiting oxidative stress and reducing inflammation

Journal10.1186/s13019-024-03020-2

ApplicationWB

IF1.5

SpeciesMouse

PMID39354500