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EEA1 Rabbit monoclonal antibody（KU）

货号: BS40173

价格：￥ 1200

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS40173

Product Name :EEA1 Rabbit monoclonal antibody（KU）

Swiss-Prot :Q15075

Host :Rabbit

Reactivity :Human Mouse Rat

Applications :WB ICC/IF

Application_all :WB 1:500~1:2000 ICC/IF 1:50~1:200

Background :EEA1 is an early endosomal marker and a Rab5 effector protein essential for early endosomal membrane fusion and trafficking (1-2). The carboxy terminus of EEA1 contains a FYVE domain which binds to phosphatidylinositol-3-phosphate (PtdIns(3)P), targeting EEA1 to early endosomes (3). The stable association of EEA1 with the endosomal membrane is regulated by PI3 kinase, Rab5 and calcium/calmodulin (4-6). Once on the membrane, EEA1 interacts with Rab5, NSF and syntaxin 13 to promote early endosomal membrane docking and fusion (7).

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Purification&Purity :Affinity-chromatography

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :EEA1 Antibody detects endogenous levels of total EEA1

BiowMW :170kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Early endosome antigen 1; EEA1; MST105; ZFYVE2;

Immunogen :A synthesized peptide derived from human EEA1

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of EEA1 expression in (1) HeLa cell lysate; (2) NIH/3T3 cell lysate.

免疫沉淀（IP）