Product Name :c-Maf Rabbit monoclonal antibody（KU）
Reactivity :Human Mouse Rat
Application_all :IHC 1:50~1:200
Background :Acts as a transcriptional activator or repressor. Involved in embryonic lens fiber cell development. Recruits the transcriptional coactivators CREBBP and/or EP300 to crystallin promoters leading to up-regulation of crystallin gene during lens fiber cell differentiation. Activates the expression of IL4 in T helper 2 (Th2) cells. Increases T-cell susceptibility to apoptosis by interacting with MYB and decreasing BCL2 expression. Together with PAX6, transactivates strongly the glucagon gene promoter through the G1 element.
Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Purification&Purity :Affinity-chromatography
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :c-Maf Antibody detects endogenous levels of total c-Maf
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :Avian musculoaponeurotic fibrosarcoma (MAF) protooncogene; c-MAF; c-maf proto-oncogene; cMaf; MAF; MGC71685; Proto-oncogene c-Maf;
Immunogen :A synthesized peptide derived from human c-Maf
