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Phospho-p53 (S376) Rabbit monoclonal antibody（KU）

货号: BS40152

价格：￥ 1200

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS40152

Product Name :Phospho-p53 (S376) Rabbit monoclonal antibody（KU）

Swiss-Prot :P04637

Host :Rabbit

Reactivity :Human

Applications :WB

Application_all :WB 1:500~1:2000

Background :Plays an essential role in the regulation of cell cycle, specifically in the transition from G0 to G1. It is found in very low levels in normal cells, however, in a variety of transformed cell lines, it is expressed in high amounts, and believed to contribute to transformation and malignancy. p53 is a DNA-binding protein containing DNA-binding, oligomerization and transcription activation domains. It is postulated to bind as a tetramer to a p53-binding site and activate expression of downstream genes that inhibit growth and/or invasion, and thus function as a tumor suppressor.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Purification&Purity :Affinity-chromatography

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Phospho-p53 (S376) Antibody detects endogenous levels of total Phospho-p53 (S376)

BiowMW :53kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Antigen NY-CO-13, Cellular tumor antigen p53, Phosphoprotein p53, TP53, Tumor suppressor p53

Immunogen :A synthesized peptide derived from human Phospho-p53 (S376)

Conjugate :Unconjugated

Modification :Phosphorylated

Western blot analysis of Phospho-p53 (S376) in HEK293 cell lysates treated with Calyculin A and Okadaic Acid.

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