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LRRK2 Rabbit monoclonal antibody（KU）

货号: BS40072

价格：￥ 1200

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS40072

Product Name :LRRK2 Rabbit monoclonal antibody（KU）

Swiss-Prot :Q5S007

Host :Rabbit

Reactivity :Human Mouse

Applications :WB IHC ICC/IF

Application_all :WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200

Background :LRRK2 positively regulates autophagy through a calcium-dependent activation of the CaMKK/AMPK signaling pathway. The process involves activation of nicotinic acid adenine dinucleotide phosphate (NAADP) receptors, increase in lysosomal pH, and calcium release from lysosomes. Together with RAB29, plays a role in the retrograde trafficking pathway for recycling proteins, such as mannose 6 phosphate receptor (M6PR), between lysosomes and the Golgi apparatus in a retromer-dependent manner.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Purification&Purity :Affinity-chromatography

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :LRRK2 Antibody detects endogenous levels of total LRRK2

BiowMW :286kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Leucine-rich repeat serine/threonine-protein kinase 2; Dardarin; PARK8; ROCO2; RIPK7; LRRK2

Immunogen :A synthesized peptide derived from human LRRK2

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of LRRK2 expression in GFP-LRRK2 lysate.

免疫沉淀（IP）