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Phospho-LAT (Y220) Rabbit monoclonal antibody（KU）

货号: BS40034

价格：￥ 1200

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS40034

Product Name :Phospho-LAT (Y220) Rabbit monoclonal antibody（KU）

Swiss-Prot :O43561

Host :Rabbit

Reactivity :Human Mouse Rat

Applications :WB IHC ICC/IF IP

Application_all :WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:30

Background :Required for TCR (T-cell antigen receptor)- and pre-TCR-mediated signaling, both in mature T-cells and during their development. Involved in FCGR3 (low affinity immunoglobulin gamma Fc region receptor III)-mediated signaling in natural killer cells and FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Couples activation of these receptors and their associated kinases with distal intracellular events such as mobilization of intracellular calcium stores, PKC activation, MAPK activation or cytoskeletal reorganization through the recruitment of PLCG1, GRB2, GRAP2, and other signaling molecules.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Purification&Purity :Affinity-chromatography

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Phospho-LAT LAT (Y220) Antibody detects endogenous levels of total Phospho-LAT (Y220)

BiowMW :38kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :36 kDa phospho-tyrosine adaptor protein; LAT1; lat; pp36

Immunogen :A synthesized peptide derived from human Phospho-LAT (Y220)

Conjugate :Unconjugated

Modification :Phosphorylated

Western blot analysis of Phospho-LAT (Y220) in Jurkat cell treated with CD3 lysate.

免疫沉淀（IP）