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MFAP2 polyclonal antibody

货号: BS3985

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS3985

Product Name :MFAP2 polyclonal antibody

Swiss-Prot :P55001

Host :Rabbit

Reactivity :Human,Rat,Mouse

Applications :WB

Application_all :WB: 1:1000~1:2000

Background :Elastic fibers endow loose connective tissue with a resilience that complements the tensile strength of collagenous fibers. They are composed of the protein elastin and a network of 10-12 nm microfibrils, which contain several glycoproteins, including fibrillin-1, fibrillin-2 and the microfibril-associated glycoproteins MAGP-1 and MAGP-2. During elastogenesis, MAGP-1 and MAGP-2 bind the fibrillins to tropoelastin in the extracellular matrix of several elastic and non-elastic tissues. MAGP-1 is an O-Glycosylated protein secreted to the extracellular space and the extracellular matrix. MAGP-1 associates with Biglycan and elastin in a ternary complex. It can make intermolecular disulfide bonds with other MAGP-1 molecules or with other microfibril components and may form transglutaminase cross-links. Underexpression and overexpression of the Zebrafish homolog of MAGP-1 (Magp-1) protein levels demonstrate the critical role of MAGP-1 in vascular development.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :MFAP2 polyclonal antibody detects endogenous levels of MFAP2 protein.

BiowMW :~ 25 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Microfibrillar-associated protein 2; MFAP-2; Microfibril-associated glycoprotein 1; MAGP; MAGP-1; MFAP2; MAGP1

Immunogen :Synthetic peptide, corresponding to Human MFAP2.

Conjugate :Unconjugated

Modification :Unmodified

Western blot (WB) analysis of MFAP2 polyclonal antibody at 1:1000 dilution Lane1:Hela whole cell lysate(30ug) Lane2:MCF-7 whole cell lysate(30ug) Lane3:The Brain tissue lysate of Mouse(30ug) Lane4:The Lung tissue lysate of Rat(30ug)