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HMOX1 polyclonal antibody(KU)

货号: BS3978

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS3978

Product Name :HMOX1 polyclonal antibody(KU)

Swiss-Prot :P09601

Host :Rabbit

Reactivity :Human,Rat,Mouse

Applications :WB IP

Application_all :WB: 1:1000~1:2000 IP: 1:50~1:200

Background :Heme oxygenase (HO) is the rate-limiting enzyme in the catabolism of heme that results in the release of carbon monoxide, iron, and biliverdin. The products of this enzymatic reaction play important biological roles in antioxidant, anti-inflammatory, and cytoprotective functions. HO comprises two isozymes, including the constitutively expressed HO-2 isozyme and the inducible HO-1 isozyme. Inducible HO-1 is expressed as an adaptive response to several stimuli, including heme, metals, and hormones. The induction of HO-1 has been implicated in numerous disease states, such as transplant rejection, hypertension, atherosclerosis, Alzheimer's disease, endotoxic shock, diabetes, inflammation, and neurological disorders.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :HMOX1 polyclonal antibody detects endogenous levels of HMOX1 protein.

BiowMW :~ 32 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Heme oxygenase 1; HO-1; Heme oxygenase 1 soluble form; HMOX1; HO; HO1

Immunogen :Recombinant protein of human HMOX1.

Conjugate :Unconjugated

Modification :Unmodified

Western blot (WB) analysis of HMOX1 polyclonal antibody at 1:1000 dilution Lane1:HepG2 whole cell lysate(30ug) Lane2:A549 whole cell lysate(30ug) Lane3:A2780 whole cell lysate(30ug) Lane4:The Spleen tissue lysate of Mouse(30ug) Lane5:PMVEC whole cell lysate(30ug)

Hepatocyte-Specific HuR Protects Against Acetaminophen-Induced Liver Injury in Mice

Journal10.1111/jcmm.70246

ApplicationWB

IF4.3

SpeciesMouse

PMID39614424