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SFRS15 (V641) polyclonal antibody（KU）

货号: BS3953

价格：￥ 1140

货期：现货（1-2个工作日）

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详细信息检测数据实验指南文献

No. :BS3953

Product Name :SFRS15 (V641) polyclonal antibody（KU）

Swiss-Prot :O95104

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IHC

Application_all :WB: 1:500~1:1000 IHC: 1:50~1:200

Background :The family of SR factors all contain one or more RNA recognition motifs (RRM) and an SR-rich domain. They are not only essential for constitutive splicing, but also regulate splicing in a concentration-dependent manner by influencing the selection of alternative splice sites. Splicing factor arginine/serine-rich 15 (SFRS15), also designated CTD-binding SR-like protein RA4, contains one RRM and one SR-rich domains. SFRS15 interacts with C-terminal repetitive domain (CTD) of Pol II and is believed to functionally and physically link transcription and pre-mRNA processing. Localized to the nucleus, SFRS15 is expressed as two isoforms produced by alternative splicing.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :SFRS15 (V641) polyclonal antibody detects endogenous levels of SFRS15 protein.

BiowMW :~ 170 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Splicing factor, arginine/serine-rich 15; CTD-binding SR-like protein RA4; SR-related and CTD-associated factor 4; SCAF4; KIAA1172; SFRS15

Immunogen :Synthetic peptide, corresponding to amino acids 611-660 of Human SFRS15.

Conjugate :Unconjugated

Modification :Unmodified

Western blot (WB) analysis of SFRS15 (V641) pAb at 1:1000 dilution Lane1:C6 whole cell lysate(40ug) Lane2:CT26 whole cell lysate(40ug) Lane3:HCT116 whole cell lysate(40ug) Lane4:SGC7901 whole cell lysate(40ug) Lane5:HEK293T whole cell lysate(20ug)

Immunohistochemistry (IHC) analyzes of SFRS15 (V641) pAb in paraffin-embedded human colorectal carcinoma tissue at 1:50.