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Septin 2 (L136) polyclonal antibody（KU）

货号: BS3936

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS3936

Product Name :Septin 2 (L136) polyclonal antibody（KU）

Swiss-Prot :Q15019

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB

Application_all :WB: 1:500~1:1000

Background :The transcriptional regulation of all septins is complex, resulting in alternatively spliced variants. At least three septins (Septin 1, 2 and 4) are associated with a Tau-based paired helical filament core and may contribute to the formation of neurofibrillary tangle as integral constituents of paired helical filaments. Septin 3 (G-Septin), a GTPbinding protein, is highly expressed in brain and is regulated by protein kinase G in neurons. The human SEPT4 (H5/PNUTL2/CDCrREL-2) gene encodes ARTS (for apoptosis-related protein in the TGF β signaling pathway), which is expressed in many cells and acts to enhance cell death induced by TGF β or, to a lesser extent, by other apoptotic agents. ARTS is localized to mitochondria and translocates to the nucleus when apoptosis occurs.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Septin 2 (L136) polyclonal antibody detects endogenous levels of Septin 2 protein.

BiowMW :~ 45 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :DIFF6; hNEDD5; KIAA0158; Neural precursor cell expressed developmentally down regulated protein 5; Pnutl3; Protein NEDD5; SEPT2

Immunogen :Synthetic peptide, corresponding to amino acids 108-157 of Human Septin 2.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of SEPT2 pAb at 1:1000 dilution Lane1:HepG2 whole cell lysate(40ug) Lane2:HEK293T whole cell lysate(40ug) Lane3:AML-12 whole cell lysate(40ug) Lane4:PC12 whole cell lysate(40ug)