Product Name :MEK-7 (I264) polyclonal antibody
Reactivity :Human,Mouse,Rat
Application_all :IHC: 1:50~1:200
Background :Mitogen Activated Protein Kinase Kinase 7 (MEK 7 or MKK 7) is a 38 kDa member of a tyrosine/threonine protein kinase family that activates the c Jun NH2-terminal kinases (JNK), which is part of the inflammation/stress signaling pathway. Phosphorylation of MEK 7 by MEKK 1 on serine 271 and threonine 275 in the catalytic domain activates the protein and enables MEK 7 to phosphorylate JNK.
Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :MEK-7 (I264) polyclonal antibody detects endogenous levels of MEK-7 protein.
Note :For research use only, not for use in diagnostic procedure.
Pathway :SAPK JNK Signaling Cascades,
Alternative Name :Mitogen Activated Protein Kinase kinase 7; c-Jun N-terminal kinase kinase 2; JNK activating kinase 2; Jnkk 2; Jnkk2; MAP2K7; MAPKK-7; MKK 7; MKK-7; PRKMK 7; PRKMK7; Sek-2; Dual specificity mitogen activated protein kinase kinase 7; JNK kinase 2; Jnkk
Immunogen :Synthetic peptide, corresponding to amino acids 241-290 of Human MEK-7.
Modification :Unmodification
