Product Name :Rad51 (T309) polyclonal antibody
Application_all :WB: 1:500~1:1000
IHC: 1:50~1:200
Background :Rad51 is a recombinase that is essential for homologous recombination and double-strand break repair. It binds to single and double-stranded DNA, and has DNA-dependent ATPase activity. Rad51 unwinds duplex DNA and forms helical nucleoprotein filaments in a manner that is controlled through the action of DNA helicases that counteract nucleofilament formation. Rad51 interacts with BRCA1 and BRCA2, and also plays a role in p53-mediated signalling. Interaction of Rad51 with Chk1 kinase may occur in response to Chk1 phosphorylation
Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Rad51 (T309) polyclonal antibody detects endogenous levels of Rad51 protein.
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :BRCC5; DNA repair protein RAD51 homolog 1; E coli RecA homolog; HGNC:9817; HRAD51; Homolog of E coli RecA; HsRad51; HsT16930; RAD51 S cerevisiae homolog; RAD51 homolog S. cerevisiae; RAD51A; RECA; Rad 51; RecA homolog E. coli; RecA like protein;
Immunogen :Synthetic peptide, corresponding to amino acids 280-330 of Human Rad51.
Modification :Unmodification
