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Neuropilin-2 (M373) polyclonal antibody（KU）

货号: BS3687

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS3687

Product Name :Neuropilin-2 (M373) polyclonal antibody（KU）

Swiss-Prot :O60462

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB

Application_all :WB: 1:500~1:1000

Background :Neuropilin is a type I transmembrane receptor that has been implicated in aspects of axon growth and guidance and has been shown to act as a high affinity receptor for class III semaphorins and vascular endothelial growth factor (VEGF). A closely related protein, neuropilin-2, shares a common domain structure and signifcant homology with neuropilin and also acts as a receptor for the class III semaphorins and VEGF. Both neuropilins are involved in regulating many physiological pathways including axonal guidance and angiogenesis, however they exhibit differential expression in the adult vasculature. Neuropilin-2 is polysialylated and expressed on the surface of dendritic cells. It is also expressed by venous and lymphatic endothelium. Neuropilin is expressed predominantly by arterial endothelium.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Neuropilin-2 (M373) polyclonal antibody detects endogenous levels of Neuropilin-2 protein.

BiowMW :~ 120 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Neuropilin-2; Vascular endothelial cell growth factor 165 receptor 2; VEGF165R2; NRP2

Immunogen :Synthetic peptide, corresponding to amino acids 341-390 of Human Neuropilin-2.

Conjugate :Unconjugated

Modification :Unmodified

Western blot (WB) analysis of Neuropilin-2 (M373) pAb at 1:500 dilution Lane1:PC3 whole cell lysate(40ug) Lane2:HEK293T whole cell lysate(20ug) Lane3:A549 whole cell lysate(20ug) Lane4:PC12 whole cell lysate(40ug) Lane5:The Kidney tissue lysate of Mouse(40ug)

Altered expression of hyperpolarization-activated cyclic nucleotide-gated channels and microRNA-1 and -133 in patients with age-associated atrial fibrillation

JournalMolecular Medicine Reports

ApplicationWB

IF2.952

SpeciesHuman

PMID26005035