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Synapsin I (Y3) polyclonal antibody

货号: BS3667

价格：￥ 1140

货期：现货（1-2个工作日）

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详细信息检测数据实验指南文献

No. :BS3667

Product Name :Synapsin I (Y3) polyclonal antibody

Swiss-Prot :P17600

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IHC IF

Application_all :WB: 1:500~1:1000 IHC: 1:50~1:200 IF: 1:50~1:200

Background :Synapsin I is a member of the synapsin family. Synapsins are neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. This member of the synapsin family plays a role in regulation of axonogenesis and synaptogenesis. The protein serves as a substrate for several different protein kinases and phosphorylation may function in the regulation of this protein in the nerve terminal. Mutations of the Synapsin I gene may be associated with X linked disorders with primary neuronal degeneration such as Rett syndrome.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Synapsin I (Y3) polyclonal antibody detects endogenous levels of Synapsin I protein.

BiowMW :~ 80 kDa

Note :For research use only, not for use in diagnostic procedure.

Pathway :Neuronal and Glial Cell Marker Atlas,

Alternative Name :Synapsin-1; Synapsin 1; Synapsin1; Brain protein 4.1; Synapsin I; SYN1

Immunogen :Synthetic peptide, corresponding to the N-terminus of Human Synapsin I.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analyzes of Synapsin I (Y3) polyclonal antibody in extracts from hela cells.

Immunohistochemistry (IHC) analyzes of Synapsin I (Y3) pAb in paraffin-embedded human brain tissue.

Early administration of tumor necrosis factor-alpha antagonist promotes survival of transplanted neural stem cells and axon myelination after spinal cord injury in rats

JournalBrain Research

ApplicationWB

IF2.929

SpeciesRat

PMID24887643
Improved synaptic and cognitive function in aged 3 × Tg-AD mice with reduced amyloid-β after immunotherapy with a novel recombinant 6Aβ15-TF chimeric vaccine

JournalClinical Immunology

ApplicationWB

IF3.969

SpeciesMouse

PMID29803820
Exosomes derived from bone-marrow mesenchymal stem cells alleviate cognitive decline in AD-like mice by improving BDNF-related neuropathology

JournalJournal of Neuroinflammation

ApplicationWB

IF8.322

SpeciesMouse

PMID35130907
Bilateral intracerebroventricular injection of streptozotocin induces AD-like behavioral impairments and neuropathological features in mice: Involved with the fundamental role of neuroinflammation

JournalBIOMEDICINE & PHARMACOTHERAPY

ApplicationWB

IF7.419

SpeciesMouse

PMID35834993
Effect of Probiotic Fungi against Cognitive Impairment in Mice via Regulation of the Fungal Microbiota–Gut–Brain Axis

JournalJOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

ApplicationIF,WB

IF5.895

SpeciesMouse

PMID35833673