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MyD88 (V220) polyclonal antibody

货号: BS3521

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS3521

Product Name :MyD88 (V220) polyclonal antibody

Swiss-Prot :Q99836

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IHC

Application_all :WB: 1:500~1:1000 IHC: 1:50~1:200

Background :The myeloid differentiation protein MyD88 was originally characterized as a protein upregulated in myeloleukemic cells following IL-6-induced growth arrest and terminal differentiation. MyD88 is now known to function as an adaptor protein for the association of IRAK with the IL-1 receptor. MyD88 is functionally homologous to the adaptor protein tube in the Toll signaling pathway of Drosophilia, and both proteins are members of the Toll/IL-1R superfamily. MyD88 contains a characteristic N-terminal death domain that is essential for NFκB activation and an adjacent Toll/IL-1R homology domain (TIR domain). Collectively, these domains enable the protein-protein interactions of MyD88 with IRAK and the IL-1 receptor complex.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :MyD88 (V220) polyclonal antibody detects endogenous levels of MyD88 protein.

BiowMW :~ 35 kDa

Note :For research use only, not for use in diagnostic procedure.

Pathway :Toll-like Receptor signaling,

Alternative Name :Myeloid differentiation primary response protein MyD88

Immunogen :Synthetic peptide, corresponding to amino acids 186-236 of Human MyD88.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of MyD88 (V220) polyclonal antibody at 1:500 dilution Lane1:MCF-7 whole cell lysate Lane2:Raw264.7 whole cell lysate Lane3:PC12 whole cell lysate

Immunohistochemistry (IHC) analyzes of MyD88 (V220) pAb in paraffin-embedded human brain tissue.

Toll-Like Receptors 2 and 4 Predict New-Onset Atrial Fibrillation in Acute Myocardial Infarction Patients

JournalInternational Heart Journal

ApplicationWB

IF1.906

SpeciesHuman

PMID29375116
Effects of borneol combined with astragaloside IV and Panax notoginseng saponins regulation of microglia polarization to promote neurogenesis after cerebral ischaemia

JournalJOURNAL OF PHARMACY AND PHARMACOLOGY

ApplicationWB

IF4.81

SpeciesRat

PMID37185938