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Integrin αV (P804) polyclonal antibody（KU）

货号: BS3513

价格：￥ 1140

货期：现货（1-2个工作日）

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详细信息检测数据实验指南文献

No. :BS3513

Product Name :Integrin αV (P804) polyclonal antibody（KU）

Swiss-Prot :P06756

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IHC

Application_all :WB: 1:500~1:1000 IHC: 1:50~1:200

Background :The integrin family contains at least 18 α and 8 β subunits that form 24 known integrins with distinct tissue distribution and overlaping ligand specificities. Integrins not only transmit signals to cells in response to the extracellular environment (outside-in signaling), but also sense intracellular cues to alter their interaction with extracellular environment (inside-out signaling).Several αV subfamily members, including αVβ3, αVβ5, αVβ1, are highly expressed in active endothelial cells and cancer cells where they play a critical role in angiogenesis and tumor metastasis.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Integrin αV (P804) polyclonal antibody detects endogenous levels of Integrin αV protein.

BiowMW :~ 116 kDa

Note :For research use only, not for use in diagnostic procedure.

Pathway :Tumor Angiogenesis,Contribution of ECM and Cytoskeletal Factors to EMT,

Alternative Name :Integrin alpha-V; Vitronectin receptor subunit alpha; CD51; Integrin alpha-V heavy chain; Integrin alpha-V light chain; ITGAV; MSK8; VNRA

Immunogen :Synthetic peptide, corresponding to amino acids 771-820 of Human Integrin αV.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of Integrin αV (P804) pAb at 1:1000 dilution Lane1:HEK293T whole cell lysate(40ug) Lane2:C6 whole cell lysate(20ug) Lane3:CT26 whole cell lysate(40ug)

Immunohistochemistry (IHC) analyzes of Integrin αV (P804) pAb in paraffin-embedded human brain tissue.

Herbal compound Teng‑Long‑Bu‑Zhong‑Tang inhibits metastasis in human RKO colon carcinoma

JournalOncology Letters

ApplicationIHC

IF2.311

SpeciesMouse

PMID29344222